![]() Can be given for moderate-to-severe chronic pain in certain populations, such as the terminally ill. ![]() Considered the analgesic of choice for ST-segment-elevation MI (STEMI). May be used to treat severe acute pain.It may also be called an opiate agonist, an opioid analgesic, or an opioid. Morphine belongs to the group of medicines known as narcotic analgesics.Morphine has very strong pain-relieving effects. When morphine binds to MOP receptors it indirectly stimulates descending inhibitory pathways and 5-hydroxytryptamine and enkephalin-containing neurons that ultimately results in a reduction in nerve transmission from the periphery to the brain. Activation of MOP receptors in the midbrain is thought to be a major mechanism of opioid-induced analgesia. Morphine works by binding mainly to mu-opioid (MOP) receptors in the brain and the periphery, including the stomach.Morphine is an analgesic (pain-reliever) that may be used to treat moderate-to-severe pain that is unresponsive to other, less potent, pain-relieving medicines.Medically reviewed by Carmen Fookes, BPharm.
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